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Invitrogen
AP4S1 Polyclonal Antibody
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产品信息
PA5-59011
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LDEYFSRVSE LDVSFFNTVF HSTWQMHSGP YQEPIDELPK ICSALEPQQT CFSPDSSSFK GAASTT
Highest antigen sequence identity to the following orthologs: Mouse - 34%, Rat - 24%.
靶标信息
This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in this gene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adaptor related protein complex 4, sigma 1 subunit; Adaptor-related protein complex 4 subunit sigma-1; adaptor-related protein complex 4, sigma 1 subunit; AP-4 adapter complex subunit sigma-1; AP-4 adaptor complex subunit sigma-1; AP-4 complex subunit sigma-1; clathrin-associated/assembly/adaptor protein, sigma 4; Sigma-1 subunit of AP-4; Sigma-4-adaptin; Sigma4-adaptin
基因别名: AP47B; AP4S1; CLA20; CLAPS4; CPSQ6; SPG52
UniProt ID: (Human) Q9Y587
Entrez Gene ID: (Human) 11154
