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Product Details
PA5-42818
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human APOBEC3B
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2576723
Product Specific Information
Peptide sequence: NQLPAYKCFQ ITWFVSWTPC PDCVAKLAEF LSEHPNVTLT ISAARLYYYW
Sequence homology: Cow: 82%; Horse: 91%; Human: 100%; Pig: 92%; Rabbit: 82%; Rat: 91%; Zebrafish: 90%
Target Information
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: A3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; bK150C 2.2; cytidine deaminase; DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 2; phorbolin 3; Phorbolin-1-related protein; Phorbolin-2/3; probable DNA dC->dU-editing enzyme APOBEC-3B
Gene Aliases: A3B; APOBEC1L; APOBEC3B; ARCD3; ARP4; bK150C2.2; DJ742C19.2; PHRBNL
UniProt ID: (Human) Q9UH17
Entrez Gene ID: (Human) 9582
Molecular Function:
RNA processing factor
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