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Proteintech
APPL2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
14294-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
APPL2 Fusion Protein Ag5626 (314-664 aa encoded by BC033731)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.27 mg/mL
规格
40.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: RGAVAGGLI QDLDNCSVMA VDCEDRRYCF QITTPNGKSG IILQAESRKE NEEWICAINN ISRQIYLTDN PEAVAIKLNQ TALQAVTPIT SFGKKQESSC PSQNLKNSEM ENENDKIVPK VTASLPEAEE LIAPGTPIQF DIVLPATEFL DQNRGSRRTN PFGETEDESF PEAEDSLLQQ MFIVRFLGSM AVKTDSTTEV IYEAMRQVLA ARAIHNIFRM TESHLMVTSQ SLRLIDPQTQ VSRANFELTS VTQFAAHQEN KRLVGFVIRV PESTGEESLS TYIFESNSEG EKICYAINLG KEIIEVQKDP EALAQLMLSI PLTNDGKYVL LNDQPDDDDG NPNEHRGAES EA (314-664 aa encoded by BC033731)
靶标信息
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: adapter protein containing PH domain, PTB domain and leucine zipper motif 2; adaptor protein; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DIP13 beta; dip13-beta; unnamed protein product
基因别名: DIP13 beta; DIP13B; Dip3 beta; Dip3b; RGD1563028
UniProt ID: (Human) Q8NEU8, (Mouse) Q8K3G9, (Rat) B4F779
Entrez Gene ID: (Human) 55198, (Mouse) 216190, (Rat) 362860
diet induced thermogenesis
protein import into nucleus
cell surface receptor signaling pathway
transforming growth factor beta receptor signaling pathway
cell proliferation
cold acclimation
regulation of fibroblast migration
signaling
adiponectin-activated signaling pathway
regulation of toll-like receptor 4 signaling pathway
cellular response to hepatocyte growth factor stimulus
homeostatic process
glucose homeostasis
regulation of innate immune response
negative regulation of fatty acid oxidation
negative regulation of glucose import
regulation of phagocytosis
negative regulation of neurogenesis
protein homotetramerization
positive regulation of phagocytosis, engulfment
positive regulation of cold-induced thermogenesis
regulation of cytokine production involved in inflammatory response
negative regulation of cytokine production involved in inflammatory response
negative regulation of cellular response to insulin stimulus
positive regulation of macropinocytosis
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
regulation of G1/S transition of mitotic cell cycle
negative regulation of neural precursor cell proliferation
signal transduction
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