FIGURE: 1 / 4
Cellular Location: Golgi apparatus, Lipid-anchor, Membrane
ADP-ribosylation factor 4D is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4D is closely similar to ARL4A and ARL4C and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in membrane-associated intracellular trafficking. Mutations in this gene have been associated with Bardet-Biedl syndrome.
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Protein Aliases: ADP-ribosylation factor like GTPase 4D; ADP-ribosylation factor-like 4D; ADP-ribosylation factor-like 5; ADP-ribosylation factor-like 6; ADP-ribosylation factor-like protein 4D; ADP-ribosylation factor-like protein 4L; ADP-ribosylation factor-like protein 5; neuroprotective protein 2
Gene Aliases: 1110036H21Rik; ARF4L; Arfl4; ARL4D; Arl5; ARL6; AW456149
Molecular Function: G-protein