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产品信息
PA5-50200
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:25-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Full length fusion protein of Human ARL6 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.7 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2635653 |
产品详细信息
The antibody detects endogenous levels of total ARL6 protein.
靶标信息
The protein encoded by this gene belongs to the ARF-like (ADP ribosylation factor-like) sub-family of the ARF family of GTP-binding proteins which are involved in regulation of intracellular traffic. Mutations in this gene are associated with Bardet-Biedl syndrome (BBS). Alternative splicing results in multiple transcript variants of this gene. A vision-specific transcript encoding a different protein has been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein
基因别名: ARL6; BBS3; RP55
UniProt ID: (Human) Q9H0F7
Entrez Gene ID: (Human) 84100
分子生物学功能:
G-protein
protein targeting to membrane
small GTPase mediated signal transduction
determination of left/right symmetry
brain development
visual perception
regulation of smoothened signaling pathway
retina layer formation
Wnt signaling pathway
melanosome transport
cilium assembly
fat cell differentiation
intermembrane transport
protein polymerization
protein localization to cilium
protein localization to nonmotile primary cilium
