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产品信息
PA5-50798
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:100-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Full length fusion protein of Human ARMC10 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.6 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.4, with 40% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2636250 |
产品详细信息
The antibody detects endogenous levels of total ARMC10 protein.
靶标信息
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Armadillo repeat-containing protein 10; specific splicing variant involved in hepatocarcinogenesis; Splicing variant involved in hepatocarcinogenesis protein
基因别名: ARMC10; PNAS-112; PNAS112; PSEC0198; SVH
UniProt ID: (Human) Q8N2F6
Entrez Gene ID: (Human) 83787
