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Proteintech
ASCC1 Polyclonal Antibody
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产品信息
12301-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASCC1 Fusion Protein Ag2946 (1-355 aa encoded by BC012291)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEVLRPQLI RIDGRNYRKN PVQEQTYQHE EDEEDFYQGS MECADEPCDA YEVEQTPQGF RSTLRAPSLL YKHIVGKRGD TRKKIEMETK TSISIPKPGQ DGEIVITGQH RNGVISARTR IDVLLDTFRR KQPFTHFLAF FLNEVEVQEG FLRFQEEVLA KCSMDHGVDS SIFQNPKKLH LTIGMLVLLS EEEIQQTCEM LQQCKEEFIN DISGGKPLEV EMAGIEYMND DPGMVDVLYA KVHMKDGSNR LQELVDRVLE RFQASGLIVK EWNSVKLHAT VMNTLFRKDP NAEGRYNLYT AEGKYIFKER ESFDGRNILK LFENFYFGSL KLNSIHISQR FTVDSFGNYA SCGQID (1-355 aa encoded by B C012291)
靶标信息
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit P50; Trip4 complex subunit p50
基因别名: 1810015P09Rik; AI550520; Asc-1; ASC1p50; ASCC1; CGI-18; p50; SMABF2
UniProt ID: (Human) Q8N9N2, (Mouse) Q9D8Z1
Entrez Gene ID: (Human) 51008, (Rat) 294512, (Mouse) 69090
