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Invitrogen
ASCL4 Polyclonal Antibody
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ASCL4 Antibody (PA5-89830) in IHC (P)
Immunohistochemistry analysis of ASCL4 in paraffin-embedded human breast cancer using. Samples were incubated with ASCL4 Polyclonal antibody (Product # PA5-89830) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-89830
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.53 mg/mL
规格
53 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A431, A549, SGC-7901, 293T, MCF7; Cellular Location: Nucleus
Immunogen sequence: METRKPAERL ALPYSLRTAP LGVPGTLPGL PRRDPLRVAL RLDAACWEWA RSGCARGWQY LPVPLDSAFE
靶标信息
ASCL4, a basic helix-loop-helix transcription factor, is essential for the determination of cell fate and the development and differentiation of numerous tissues. It could be a transcriptional regulator involved in skin development.Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: achaete-scute complex homolog 4; achaete-scute complex-like 4; Achaete-scute homolog 4; Achaete-scute-like protein 4; ASH-4; basic helix-loop-helix protein; bHLHa44; Class A basic helix-loop-helix protein 44; class II bHLH protein ASCL4
基因别名: 1700054F16Rik; ASCL4; ASH-4; BHLHA44; HASH4
Entrez Gene ID: (Human) 121549, (Mouse) 67341, (Rat) 299687
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
protein dimerization activity
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