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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（石蜡） (IHC (P)) |
1:500-1:2,000 | - |
酶联免疫吸附实验 (ELISA) |
1:5,000-1:10,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Mouse ASGPR1/ASGR1 protein |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein A, Antigen affinity chromatography |
保存液 |
PBS |
内含物 |
no preservative |
保存条件 |
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
RRID |
AB_2788534 |
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse ASGPR1/ASGR1.
The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ASGP-R 1; ASGPR 1; Asialoglycoprotein receptor 1; Hepatic lectin 1; HL-1
基因别名: ASGPR1; Asgr; Asgr-1; Asgr1; HL-1
UniProt ID: (Mouse) P34927
Entrez Gene ID: (Mouse) 11889
分子生物学功能:
membrane traffic protein
