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Proteintech
ASGR1 Monoclonal Antibody (1G5F5)
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产品信息
66692-1-IG
产品规格
种属反应
Human,
Mouse,
Pig
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1G5F5
抗原
ASGR1 Fusion Protein Ag2310 (1-291 aa encoded by BC032130)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MTKEYQDLQ HLDNEESDHH QLRKGPPPPQ PLLQRLCSGP RLLLLSLGLS LLLLVVVCVI GSQNSQLQEE LRGLRETFSN FTASTEAQVK GLSTQGGNVG RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS ERTCCPVNWV EHERSCYWFS RSGKAWADAD NYCRLEDAHL VVVTSWEEQK FVQHHIGPVN TWMGLHDQNG PWKWVDGTDY ETGFKNWRPE QPDDWYGHGL GGGEDCAHFT DDGRWNDDVC QRPYRWVCET ELDKASQEPP LL (1-291 aa encoded by BC032130)
靶标信息
The asialoglycooprotein receptor (ASGPR) is a transmembrane glycoprotein (42 kDa) which mediates binding, internalization and degradation of extracellular glycoproteins that have exposed terminal galactose residues. The receptor is expressed on the surface of the hepatocytes in a polar manner, i. e. it is present on the sinusoidal and lateral plasma membranes but not on the bile canalicular membrane. The mammalian hepatic ASGPR mediate the endocytosis and degradation of serum proteins from which terminal sialic residues have been removed. The rat asialoglycoprotein receptor (ASGPR) consists of three polypeptide subunits: rat hepatic lectin (RHL)-1, RHL-2 and RHL-3. The monoclonal antibody 8D7 recognizes a subunit-specific epitope of RHL-1 of rat ASGPR. The monoclonal antibody 8D7 is cross reactive with human ASGPR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASGP-R 1; ASGPR 1; Asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; Hepatic lectin 1; Hepatic lectin H1; HL-1
基因别名: ASGPR; ASGPR1; Asgr; Asgr-1; ASGR1; CLEC4H1; HL-1
UniProt ID: (Human) P07306, (Mouse) P34927
Entrez Gene ID: (Pig) 100625649, (Human) 432, (Mouse) 11889
