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Proteintech
ASIC4 Polyclonal Antibody
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产品信息
12003-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASIC4 Fusion Protein Ag2664 (299-647 aa encoded by BC010439)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: QLADMLKSC NFSGHHCSAS NFSVVYTRYG KCYTFNADPR SSLPSRAGGM GSGLEIMLDI QQEEYLPIWR ETNETSFEAG IRVQIHSQEE PPYIHQLGFG VSPGFQTFVS CQEQRLTYLP QPWGNCRAES ELREPELQGY SAYSVSACRL RCEKEAVLQR CHCRMVHMPD SLGGGPEGPC FCPTPCNLTR YGKEISMVRI PNRGSARYLA RKYNRNETYI RENFLVLDVF FEALTSEAME QRAAYGLSAL LGDLGGQMGL FIGASILTLL EILDYIYEVS WDRLKRVWRR PKTPLRTSTG GISTLGLQEL KEQSPCPSLG RAEGGGVSSL LPNHHHPHGP PGGLFEDFAC (299-647 aa encoded by BC010439)
靶标信息
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acid sensing (proton gated) ion channel family member 4; acid sensing ion channel family member 4; acid-sensing (proton-gated) ion channel family member 4; Acid-sensing ion channel 4; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; ASIC4; brain sodium channel 4; MGC17248; MGC24860; putative acid-sensing ion channel; spinal chord ASIC; Spinal cord ASIC
基因别名: ACCN4; ASIC4; BNAC4; Spasic
UniProt ID: (Human) Q6PIN9, (Rat) Q9JHS6, (Mouse) Q7TNS7
Entrez Gene ID: (Human) 55515, (Rat) 63882, (Mouse) 241118
