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Proteintech
ATG4D Polyclonal Antibody
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产品信息
16924-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ATG4D Fusion Protein Ag10307 (123-474 aa encoded by BC068992)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TYRRDFPPL PGGCLTSDCG WGCMLRSGQM MLAQGLLLHF LPRDWTWAEG MGLGPPELSG SASPSRYHGP ARWMPPRWAQ GAPELEQERR HRQIVSWFAD HPRAPFGLHR LVELGQSSGK KAGDWYGPSL VAHILRKAVE SCSDVTRLVV YVSQDCTVYK ADVARLVARP DPTAEWKSVV ILVPVRLGGE TLNPVYVPCV KELLRCELCL GIMGGKPRHS LYFIGYQDDF LLYLDPHYCQ PTVDVSQADF PLESFHCTSP RKMAFAKMDP SCTVGFYAGD RKEFETLCSE LTRVLSSSSA TERYPMFTLA EGHAQDHSLD DLCSQLAQPT LRLPRTGRLL RAKRPSSEDF VFL (123-474 aa encoded by BC068992)
靶标信息
Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; ATG4 autophagy related 4 homolog D; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D, cysteine peptidase; autophagy-related 4D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D; HsAPG4D
基因别名: 9830134P12Rik; APG4-D; APG4D; ATG4D; Atg4dl; AUTL4
UniProt ID: (Human) Q86TL0, (Mouse) Q8BGV9
Entrez Gene ID: (Human) 84971, (Mouse) 235040, (Rat) 686505
