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OriGene
ATIC Monoclonal Antibody (OTI2C10), TrueMAB™
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ATIC Antibody (CF504554) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC. Positive lysates LY418255 (100 µg) and LC418255 (20 µg) can be purchased separately from OriGene.
产品信息
CF504554
产品规格
种属反应
Dog,
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI2C10
抗原
Full length human recombinant protein of human ATIC produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein ATIC; bifunctional purine biosynthesis protein PURH; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
基因别名: 2610509C24Rik; AA536954; AICAR; AICARFT; ATIC; AW212393; HEL-S-70p; IMPCHASE; OK/SW-cl.86; PURH
UniProt ID: (Human) P31939, (Rat) O35567, (Mouse) Q9CWJ9
Entrez Gene ID: (Human) 471, (Dog) 488513, (Rat) 81643, (Mouse) 108147
brainstem development
nucleobase-containing compound metabolic process
'de novo' IMP biosynthetic process
nucleoside metabolic process
purine ribonucleoside monophosphate biosynthetic process
response to inorganic substance
cerebellum development
cerebral cortex development
organ regeneration
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
cell-cell adhesion
cobalamin metabolic process
ribonucleotide metabolic process
purine nucleotide biosynthetic process
metabolic process
