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OriGene
ATIC Monoclonal Antibody (OTI4A10), TrueMAB™
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产品信息
CF504570
产品规格
种属反应
Dog,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI4A10
抗原
Full length human recombinant protein of human ATIC produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein ATIC; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
基因别名: AICAR; AICARFT; ATIC; HEL-S-70p; IMPCHASE; OK/SW-cl.86; PURH
UniProt ID: (Human) P31939
Entrez Gene ID: (Human) 471, (Dog) 488513
brainstem development
nucleobase-containing compound metabolic process
'de novo' IMP biosynthetic process
nucleoside metabolic process
purine ribonucleoside monophosphate biosynthetic process
response to inorganic substance
cerebellum development
cerebral cortex development
organ regeneration
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
cell-cell adhesion
