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Invitrogen
ATMIN Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-65908
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SVSELSRAVRT NILCTVRGCG KILPNSPALN MHLVKSHRLQ DGIVNPTIRK DLKTGPKFYC CPIEGCPRGP ERPFSQFSLV KQHFMKMHAE KKHKC
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
靶标信息
The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51. ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects. It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASCIZ; ATM interactor; ATM/ATR-substrate CHK2-interacting zinc finger protein; Zinc finger protein 822
基因别名: ATMIN; KIAA0431; ZNF822
Entrez Gene ID: (Human) 23300
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