Invitrogen

ATP Citrate Lyase Recombinant Rabbit Monoclonal Antibody (2N2W3)

Name: ATP Citrate Lyase Recombinant Rabbit Monoclonal Antibody (2N2W3)
Brand: Invitrogen
SKU: MA5-51379

查看其他33个ATP Citrate Lyase抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (3)

ATP Citrate Lyase Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ATP Citrate Lyase Antibody (MA5-51379) in IHC (P)

Immunohistochemistry analysis of ATP Citrate Lyase in paraffin-embedded Human kidney. Samples were incubated with ATP Citrate Lyase Recombinant monoclonal antibody (Product # MA5-51379) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

ATP Citrate Lyase Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image ATP Citrate Lyase Recombinant Rabbit Monoclonal Antibody (2N2W3)

产品信息

MA5-51379

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

免疫组化（石蜡） (IHC (P))

1:1,000-1:5,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

2N2W3

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 752-1101 of human ACLY (NP_001087.2).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.233 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_3094258

产品详细信息

Immunogen sequence: FSSEVQFGHA GACANQASET AVAKNQALKE AGVFVPRSFD ELGEIIQSVY EDLVANGVIV PAQEVPPPTV PMDYSWAREL GLIRKPASFM TSICDERGQE LIYAGMPITE VFKEEMGIGG VLGLLWFQKR LPKYSCQFIE MCLMVTADHG PAVSGAHNTI ICARAGKDLV SSLTSGLLTI GDRFGGALDA AAKMFSKAFD SGIIPMEFVN KMKKEGKLIM GIGHRVKSIN NPDMRVQILK DYVRQHFPAT PLLDYALEVE KITTSKKPNL ILNVDGLIGV AFVDMLRNCG SFTREEADEY IDIGALNGIF VLGRSMGFIG HYLDQKRLKQ GLYRHPWDDI SYVLPEHMSM

靶标信息

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。