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Product Details
MA5-21425
产品规格
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
4H8
Immunogen
ATP11B (NP_055431, 1087 a.a. ~ 1177 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2576416
Product Specific Information
Peptide Sequence: DIIKKVFDRH LHPTSTEKAQ LTETNAGIKC LDSMCCFPEG EAACASVGRM LERVIGRCSP THISRSWSAS DPFYTNDRSI LTLSTMDSST C
Target Information
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: ATPase class VI type 11B; ATPase IR; ATPase, class VI, type 11B; P4-ATPase flippase complex alpha subunit ATP11B; Phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
Gene Aliases: ATP11B; ATPIF; ATPIR; KIAA0956
UniProt ID: (Human) Q9Y2G3
Entrez Gene ID: (Human) 23200
Molecular Function:
primary active transporter
Performance Guarantee
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