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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
2 µg/mL | - |
免疫组化 (IHC) |
10 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Synthetic peptide corresponding to residues 200-300 of human ATP13A2. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.75 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
tris glycine with 150mM NaCl |
内含物 |
0.05% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2063283 |
Suggested positive control: human and mouse brain membrane prep lysate.
Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of these lysosomes and is formed most strongly in the brain, especially in the substantia nigra, a brain region which is known to play a central role in Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AT132 antibody; ATPase type 13A2; HSA9947 antibody; Polyamine-transporting ATPase 13A2; probable cation-transporting ATPase 13A2; putative ATPase; RP1-37C10.4
基因别名: 1110012E06Rik; AA589443; ATP13A2; CLN12; HSA9947; KRPPD; PARK9
UniProt ID: (Human) Q9NQ11, (Mouse) Q9CTG6
Entrez Gene ID: (Human) 23400, (Mouse) 74772
