Proteintech

ATP1A3 (C-terminal) Polyclonal Antibody

Name: ATP1A3 (C-terminal) Polyclonal Antibody
Brand: Proteintech
SKU: 10868-1-AP

4 篇参考文献

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说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (12)

ATP1A3 (C-terminal) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 12

ATP1A3 (C-terminal) Antibody (10868-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue slide using (Product # 10868-1-AP) ATP1A3 (C-terminal) antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

ATP1A3 (C-terminal) Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

ATP1A3 (C-terminal) Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image ATP1A3 (C-terminal) Polyclonal Antibody

产品信息

10868-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:50-1:500

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ATP1A3 (C-terminal) Fusion Protein Ag1313 (665-1013 aa encoded by BC015566)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.33 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

This antibody is generated against the C-terminal region (665-1013aa) of ATP1A3 and detects the band around 100-113 kDa in SDS-PAGE.

Immunogen sequence: SEQIDEILQ NHTEIVFART SPQQKLIIVE GCQRQGAIVA VTGDGVNDSP ALKKADIGVA MGIAGSDVSK QAADMILLDD NFASIVTGVE EGRLIFDNLK KSIAYTLTSN IPEITPFLLF IMANIPLPLG TITILCIDLG TDMVPAISLA YEAAESDIMK RQPRNPRTDK LVNERLISMA YGQIGMIQAL GGFFSYFVIL AENGFLPGNL VGIRLNWDDR TVNDLEDSYG QQWTYEQRKV VEFTCHTAFF VSIVVVQWAD LIICKTRRNS VFQQGMKNKI LIFGLFEETA LAAFLSYCPG MDVALRMYPL KPSWWFCAFP YSFLIFVYDE IRKLILRRNP GGWVEKETYY (665-1013 aa encoded by BC015566)

靶标信息

The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression. The alpha-3 subunit has been found in neuronal and to skeletal and cardiac muscle, lung and stomach tissues.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: ATPase, Na+/K+ transporting, alpha 3 polypeptide; ATPase, Na+K+ transporting, alpha 3 subunit; EC 3.6.3.9; Na(+)/K(+) ATPase alpha(III) subunit; Na(+)/K(+) ATPase alpha-3 subunit; Na+, K+ activated adenosine triphosphatase alpha subunit; Na+/K+ -ATPase alpha 3 subunit; Na+/K+ ATPase 3; Sodium Potassium ATPase; Sodium pump 3; Sodium pump subunit alpha-3; sodium-potassium ATPase catalytic subunit alpha-3; sodium-potassium-ATPase, alpha 3 polypeptide; sodium/potassium-transporting ATPase alpha-3 chain; Sodium/potassium-transporting ATPase subunit alpha-3

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基因别名: AHC2; ATP1A1; ATP1A3; Atpa-2; Atpa1a3; CAPOS; DYT12; RDP

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UniProt ID: (Human) P13637, (Rat) P06687, (Mouse) Q6PIC6

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Entrez Gene ID: (Human) 478, (Rat) 24213, (Mouse) 232975

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功能