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Proteintech
ATP6V1C2 Polyclonal Antibody
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产品信息
16274-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ATP6V1C2 Fusion Protein Ag9349 (1-381 aa encoded by BC012142)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSEFWLISA PGDKENLQAL ERMNTVTSKS NLSYNTKFAI PDFKVGTLDS LVGLSDELGK LDTFAESLIR RMAQSVVEVM EDSKGKVQEH LLANGVDLTS FVTHFEWDMA KYPVKQPLVS VVDTIAKQLA QIEMDLKSRT AAYDTLKTNL ENLEKKSMGN LFTRTLSDIV SKEDFVLDSE YLVTLLVIVP KPNYSQWQKT YESLSDMVVP RSTKLITEDK EGGLFTVTLF RKVIEDFKTK AKENKFTVRE FYYDEKEIER EREEMARLLS DKKQQYGPLL RWLKVNFSEA FIAWIHIKAL RVFVESVLRY GLPVNFQAVL LQPHKKSSTK RLREVLNSVF RHLDEVAATS ILDASVEIPG LQLNNQDYFP YVYFHIDLSL LD (1-381 aa encoded by BC012142)
靶标信息
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, V1 subunit C, isoform 2; V-ATPase C2 subunit; V-ATPase subunit C 2; V-type proton ATPase subunit C 2; Vacuolar proton pump subunit C 2
基因别名: 1110038G14Rik; ATP6C2; ATP6V1C2; VMA5
UniProt ID: (Human) Q8NEY4, (Mouse) Q99L60
Entrez Gene ID: (Human) 245973, (Mouse) 68775
insulin receptor signaling pathway
ATP hydrolysis coupled proton transport
regulation of macroautophagy
positive regulation of Wnt signaling pathway
transferrin transport
ion transmembrane transport
phagosome acidification
transport
ion transport
proton transport
hydrogen ion transmembrane transport
