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Invitrogen
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Immunogen sequence: REREEMARLL SDKKQQYQTS CVALKKGSST FPDHKVKVTP LGNPDRPAAG QTDRERESEG EG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。