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Invitrogen
Abl2 Polyclonal Antibody
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产品信息
PA5-81981
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human ABL2
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
Immunogen sequence: MAGVPEDGEQ PGWPSPAKAA PVLPTTHNHK VPVLISPTLK HTPADVQLIG TDSQGNKFKL LSEHQVTSSG DKDRPRRVKP KCAPPPPPVM RLLQHPSICS DPTEEPTALT AGQSTSETQE GGKKAALGAV PISGKA
靶标信息
ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinase. The protein is highly similar to the ABL1 protein, including the tyrosine kinase, SH2 and SH3 domains, and has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells, and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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