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Proteintech
Acetylcholinesterase Polyclonal Antibody
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产品信息
17975-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Acetylcholinesterase Fusion Protein Ag12146 (1-351 aa encoded by BC094752)
偶联物
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: ACHAAMRPP QCLLHTPSLA SPLLLLLVWL LGGGVGAEGR EDAELLVTVR GGRLRGIRLK TPGGPVSAFL GIPFAEPPMG PRRFLPPEPK QPWSGVVDAT TFQSVCYQYV DTLYPGFEGT EMWNPNRELS EDCLYLNVWT PYPRPTSPTP VIVWIYGGGF YSGASSLDVY DGRFLVQAER TVLVSMNYRV GAFGFLALPG SREAPGNVGL LDQRLALQWV QENVAAFGGD PTSVTLFGES AGAASVGMHL LSPPSRGLFH RAVLQSGAPN GPWATVGMGE ARRRATQLAH LVGCPPGGTG GNDTELVACL RTRPAQVLVN HEWHVLPQES VFRFSFVPVV DGDFLSD (1-351 aa encoded by BC094752)
靶标信息
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Acetylcholinesterase; acetylcholinesterase (Yt blood group); AChE; apoptosis-related acetylcholinesterase; EC 3.1.1.7; glycolipid-anchored form of acetylcholinesterase; OTTHUMP00000211349; OTTHUMP00000211356; Yt blood group
基因别名: ACEE; ACHE; ARACHE; N-ACHE; YT
UniProt ID: (Human) P22303, (Mouse) P21836, (Rat) P37136
Entrez Gene ID: (Human) 43, (Mouse) 11423, (Rat) 83817
beta-amyloid binding
acetylcholinesterase activity
cholinesterase activity
protein binding
collagen binding
hydrolase activity
serine hydrolase activity
acetylcholine binding
protein homodimerization activity
laminin binding
protein self-association
choline binding
carboxylic ester hydrolase activity
esterase
acetylcholine catabolic process in synaptic cleft
regulation of receptor recycling
osteoblast development
DNA replication
acetylcholine catabolic process
phosphatidylcholine biosynthetic process
cell adhesion
nervous system development
synapse assembly
muscle organ development
cell proliferation
response to wounding
receptor internalization
negative regulation of synaptic transmission, cholinergic
neurotransmitter biosynthetic process
amyloid precursor protein metabolic process
neurotransmitter receptor biosynthetic process
positive regulation of protein secretion
protein tetramerization
retina development in camera-type eye
acetylcholine metabolic process
choline metabolic process
neurotransmitter catabolic process
positive regulation of axonogenesis
positive regulation of dendrite morphogenesis
neuron death
