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Invitrogen
Alpha Sarcoglycan Recombinant Rabbit Monoclonal Antibody (3W3Q10)
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产品信息
MA5-37982
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3W3Q10
抗原
A synthetic peptide corresponding to a sequence within amino acids 288-387 of human alpha Sarcoglycan (SGCA) (SGCA) (Q16586)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Rat heart, Rat skeletal muscle
Immunogen sequence: VDALVTLLVP LLVALLLTLL LAYVMCCRRE GRLKRDLATS DIQMVHHCTI HGNTEELRQM AASREVPRPL STLPMFNVHT GERLPPRVDS AQVPLILDQH
靶标信息
The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with epsilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
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生物信息学
蛋白别名: 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Alpha-sarcoglycan; Alpha-SG; Dystroglycan 2; Dystroglycan2; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); SG alpha; SG-alpha
基因别名: 50DAG; Asg; Sgca
UniProt ID: (Mouse) P82350
Entrez Gene ID: (Rat) 303468, (Mouse) 20391
