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Invitrogen
Alsin Polyclonal Antibody
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图: 1 / 4
Alsin Antibody (PA5-103595) in ICC/IF
Immunocytochemistry analysis of Alsin in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Alsin polyclonal antibody (Product # PA5-103595) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103595
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ALS2(Accession Q96Q42), corresponding to amino acid residues L204-S254.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ALS2.
靶标信息
The function of this protein remains unknown.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alsin; amyotrophic lateral sclerosis 2 (juvenile) homolog; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein; Amyotrophic lateral sclerosis 2 protein; Amyotrophic lateral sclerosis 2 protein homolog; amyotrophic lateral sclerosis protein 2 homolog; FLJ31851; MGC87187
基因别名: 3222402C23Rik; 9430073A21Rik; ALS2; ALS2CR6; Alsin; KIAA1563; mKIAA1563
UniProt ID: (Mouse) Q920R0, (Rat) P0C5Y8
Entrez Gene ID: (Mouse) 74018, (Rat) 363235
guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
Rab guanyl-nucleotide exchange factor activity
Rab GTPase binding
Rac guanyl-nucleotide exchange factor activity
identical protein binding
protein homodimerization activity
protein serine/threonine kinase activator activity
Rac GTPase binding
molecular_function
behavioral fear response
receptor recycling
response to oxidative stress
endosome organization
lysosomal transport
axonogenesis
neuromuscular junction development
locomotory behavior
protein localization
cell death
vesicle organization
endosomal transport
Rac protein signal transduction
regulation of Rho protein signal transduction
synaptic transmission, glutamatergic
regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of protein kinase activity
neuron projection morphogenesis
protein homooligomerization
positive regulation of protein serine/threonine kinase activity
in utero embryonic development
regulation of endosome size
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