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Invitrogen
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PA1-20917 detects Amylin in Human samples.
PA1-20917 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-20917 immunogen corresponds to Synthetic peptide corresponding to the N-terminal region of the human protein..
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。