Rockland

Angiopoietin 1 Polyclonal Antibody

查看其他22个Angiopoietin 1抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
Angiopoietin 1 Polyclonal Antibody

产品信息

100-401-403

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:200-1:800
-

酶联免疫吸附实验 (ELISA)

1:5,000-1:25,000
-

免疫沉淀 (IP)

1:500-1:2,000
-
产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to a N-terminus region near aa 15-45 of mouse angiopoietin 1 protein conjugated to KLH using maleimide. A residue of cysteine was added to the amino terminal end to facilitate coupling.
查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

80 mg/mL

保存液

0.02M potassium phosphate/whole serum, pH 7.2, with 0.15M NaCl

内含物

0.01% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Anti-Angiopoietin 1 is directed against mouse angiopoietin-1 and shows no reactivity with mouse angiopoietin-2. This reagent cross-reacts with human angiopoietin 1. Partially cross reactivity is noted with human angiopoietin 2.

靶标信息

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: ANG-1; Angiopoietin-1

查看更多 收起

基因别名: 1110046O21Rik; AGP1; AGPT; Ang-1; ANG1; ANGPT1; KIAA0003

查看更多 收起

UniProt ID: (Human) Q15389, (Mouse) O08538

查看更多 收起

Entrez Gene ID: (Human) 284, (Mouse) 11600

查看更多 收起

功能
Ras guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding receptor binding vascular endothelial growth factor receptor binding intercellular signal molecule
参与通路
MAPK cascade in utero embryonic development negative regulation of protein phosphorylation regulation of endothelial cell proliferation sprouting angiogenesis positive regulation of receptor internalization negative regulation of cytokine secretion involved in immune response negative regulation of cell adhesion activation of transmembrane receptor protein tyrosine kinase activity positive regulation of endothelial cell migration positive regulation of phosphatidylinositol 3-kinase signaling regulation of skeletal muscle satellite cell proliferation hemopoiesis cell differentiation heparin biosynthetic process positive regulation of protein ubiquitination cell-substrate adhesion regulation of tumor necrosis factor production positive regulation of peptidyl-serine phosphorylation protein localization to cell surface negative regulation of protein import into nucleus negative regulation of apoptotic process negative regulation of vascular permeability regulation of I-kappaB kinase/NF-kappaB signaling regulation of protein binding negative regulation of neuron apoptotic process positive regulation of blood vessel endothelial cell migration positive regulation of GTPase activity positive regulation of cell adhesion Tie signaling pathway positive regulation of peptidyl-tyrosine phosphorylation leukocyte migration positive chemotaxis positive regulation of protein kinase B signaling positive regulation of ERK1 and ERK2 cascade glomerulus vasculature development negative regulation of endothelial cell apoptotic process regulation of macrophage migration inhibitory factor signaling pathway angiogenesis ovarian follicle development patterning of blood vessels vasculogenesis endocardium morphogenesis transmembrane receptor protein tyrosine kinase signaling pathway multicellular organism development endoderm development positive regulation of vascular endothelial growth factor receptor signaling pathway protein homooligomerization cardiac muscle tissue morphogenesis vasculogenesis involved in coronary vascular morphogenesis
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持