NeoBiotechnologies

Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3764)

Name: Angiotensin I Converting Enzyme (ACE)\/CD143 Monoclonal Antibody (ACE\/3764)
Brand: NeoBiotechnologies
SKU: 1636-MSM4-P1

查看其他35个ACE抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (4)

Angiotensin I Converting Enzyme (ACE)/CD143 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

Angiotensin I Converting Enzyme (ACE)/CD143 Antibody (1636-MSM4-P1) in IHC (P)

IHC analysis of formalin-fixed, paraffin-embedded human colon carcinoma. Staining using ACE/3764 at 2 µg/mL in PBS for 30 min RT. HIER: Tris/EDTA, pH9.0, 45 min. 2nd Ab: HRP-polymer, 30 min. DAB, 5 min.

Angiotensin I Converting Enzyme (ACE)/CD143 Antibody in Peptide array (ARRAY)

Angiotensin I Converting Enzyme (ACE)/CD143 Antibody in Immunoelectrophoresis (IE)

Product Image Gallery

Immunogen image

Immunogen Image Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (ACE/3764)

产品信息

1636-MSM4-P1

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

酶联免疫吸附实验 (ELISA)

Assay-dependent

肽阵列 (Array)

Assay-dependent

免疫电泳 (IE)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

ACE/3764

抗原

Full-length recombinant human ACE/CD143 protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Antibody is stable for 24 months.

Positive Control: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Cellular Localization: Cell Surface

Specificity Comments: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

靶标信息

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes-the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: ACE; angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript; Angiotensin-converting enzyme; carboxycathepsin; CD143; CD143 antigen; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; Kininase II; MGC26566; peptidase P; testicular ECA

查看更多收起

基因别名: ACE; ACE1; CD143; DCP; DCP1; ICH; MVCD3

查看更多收起

UniProt ID: (Human) P12821

查看更多收起

Entrez Gene ID: (Human) 1636

查看更多收起

功能