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Product Details
PA1-22561
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Purified full length native apolipoprotein type C-II.
Conjugate
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.125M sodium borate, pH 8, with 0.075M NaCl, 5mM EDTA
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2057677
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: APC 2; APO C2; Apo CII; Apo-CII; APOC 2; ApoC II; APOC2 protein; ApoCII; Apolipoprotein C II; Apolipoprotein C-II; Apolipoprotein C2; Apolipoprotein CII; ApolipoproteinCII; MGC75082; ProapoC-II; Proapolipoprotein C-II
Gene Aliases: APC2; APO-CII; APOC-II; APOC2
UniProt ID: (Human) Q9UNK3
Entrez Gene ID: (Human) 344
Molecular Function:
apolipoprotein
retinoid metabolic process
positive regulation of phospholipase activity
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
lipid catabolic process
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
chylomicron remodeling
very-low-density lipoprotein particle remodeling
chylomicron remnant clearance
high-density lipoprotein particle clearance
lipoprotein metabolic process
cholesterol homeostasis
negative regulation of catalytic activity
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
positive regulation of lipoprotein lipase activity
positive regulation of phospholipid catabolic process
triglyceride homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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