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Invitrogen
Ara H1 Recombinant Mouse Monoclonal Antibody (9C1)
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Ara H1 Antibody (MA566230) in SDS-PAGE
SDS-PAGE characterization of Ara H1 under reducing conditions. Lane M: Protein marker (kDa); Lane H1-C: Purified Ara H1 Recombinant Monoclonal (Product # MA566230). Ara H1 showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-274.
产品信息
MA566230
产品规格
种属反应
Plant
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
9C1
抗原
Peanut allergen Ara H1.
偶联物
形式
Liquid
浓度
6.2 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Ara h 1 is a major allergen found in peanuts (Arachis hypogaea) and is classified as a seed storage protein. It belongs to the vicilin family of 7S globulins and is known for its strong allergenic potential, contributing significantly to peanut allergy, which is among the most common food allergies. Structurally, Ara h 1 is a glycoprotein with a molecular weight of approximately 63.5 kDa, consisting of a trimeric formation that enhances its stability and resistance to digestion. This resistance contributes to its allergenicity, as it can persist in the gastrointestinal tract and elicit immune responses. Immunologically, Ara h 1 contains multiple epitopes recognized by IgE antibodies in susceptible individuals, triggering allergic reactions. Due to its stability and prevalence, Ara h 1 is a key target in diagnostic tests and immunotherapies aimed at desensitizing allergic patients to peanuts. Ongoing research includes characterizing its structure, identifying IgE-binding sites, and understanding its role in mediating allergic responses to develop effective treatments and potentially hypoallergenic peanut varieties.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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