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Invitrogen
Ara H2 Recombinant Mouse Monoclonal Antibody (1F6)
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Ara H2 Antibody (MA566376) in SDS-PAGE
SDS-PAGE characterization of Ara H2 under reducing conditions. Lane M: Protein marker (kDa); Lane PAAH2-C: Purified Ara H2 Recombinant Monoclonal (Product # MA566376). Ara H2 showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-276.
产品信息
MA566376
产品规格
种属反应
Plant
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1F6
抗原
Peanut allergen Ara H2.
偶联物
形式
Liquid
浓度
5.6 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Ara h 2 is a major peanut allergen that belongs to the 2S albumin family, known for its high allergenic potency in individuals with peanut allergies. Structurally, Ara h 2 is a small, stable protein resistant to heat and digestive enzymes, facilitating its persistence in the gastrointestinal tract upon ingestion. This stability enhances its immunogenicity and ability to elicit strong IgE-mediated allergic responses. Ara h 2 contains specific IgE-binding epitopes that are recognized by the immune system, making it central to the allergic reaction in sensitive individuals. The identification and characterization of Ara h 2 have been pivotal in understanding peanut allergy mechanisms, including efforts to develop diagnostic assays, immunotherapy treatments, and hypoallergenic peanut varieties. Studies have focused on mapping its epitopes, analyzing its cross-reactivity with other allergens, and leveraging its properties for therapeutic interventions. Its prominence as a peanut allergen underscores the importance of Ara h 2 in allergen research, aiming to reduce the burden of peanut allergies through targeted strategies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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