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Invitrogen
Argonaute 4 Polyclonal Antibody
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Argonaute 4 Antibody (PA5-114875) in IHC (P)
Immunohistochemistry analysis of Argonaute 4 in mouse heart tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114875) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
产品信息
PA5-114875
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human AGO4(Accession Q9HCK5), corresponding to amino acid residues R58-T108.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Argonaute 4.
靶标信息
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic containing PAZ and PIWI domains, and it may play a role in short-interfering-RNA-mediated gene silencing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: argonaute 4; Argonaute RISC catalytic component 4; Argonaute4; eIF-2C 4; eIF2C 4; Eukaryotic translation initiation factor 2C 4; eukaryotic translation initiation factor 2C, 4; hAgo4; mAgo4; Piwi/Argonaute family protein meIF2C4; Protein argonaute-4
基因别名: 5730550L01Rik; AGO4; AI481660; EIF2C4; KIAA1567
UniProt ID: (Human) Q9HCK5, (Mouse) Q8CJF8
Entrez Gene ID: (Human) 192670, (Mouse) 76850, (Rat) 298533
mRNA catabolic process
Wnt signaling pathway, calcium modulating pathway
RNA secondary structure unwinding
pre-miRNA processing
posttranscriptional gene silencing by RNA
production of miRNAs involved in gene silencing by miRNA
miRNA mediated inhibition of translation
mRNA cleavage involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
phosphatidylinositol-mediated signaling
mRNA cleavage involved in gene silencing by siRNA
regulation of translation
gene silencing by RNA
translational initiation
biological_process
