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Immunogen sequence: MDSQGRKVVV CDNGTGFVKC GYAGSNFPEH IFPALVGRPI IRSTTKVGNI EIKDLMVGDE ASELRSMLEV NYPMENGIVR NWDDMKHLWD YTFGPEKLNI DTRNCKILLT EPPMNPTKNR EKIVEVMFET YQFSGVYVAI QAVLTLYAQG LLTGVVVDSG; Positive Samples: THP-1, 293T, HepG2, HeLa, C6, Mouse spleen, Mouse lung, Mouse brain, Rat kidney; Cellular Location: Cell projection, Cytoplasm, cytoskeleton
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: Actin-like protein 2; Actin-related protein 2; ARP2 actin-related protein 2 homolog
Gene Aliases: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713
Molecular Function:
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
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