This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Arylsulfatase A/ARSA.
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy, a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
蛋白别名: ARSA-I; ARSA1; Arylsulfatase A; Arylsulfatase A component B; Arylsulfatase A component C; ASA; ASNA-I; ATPase ASNA1; Cerebroside-sulfatase; EC 184.108.40.206; GET3; TRC40
基因别名: ARSA; MLD
UniProt ID: (Human) P15289
Entrez Gene ID: (Human) 410