Bethyl Laboratories

Ataxin-7 Polyclonal Antibody

Name: Ataxin-7 Polyclonal Antibody
Brand: Bethyl Laboratories
SKU: A302-638A

查看其他4个Ataxin 7抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

图: 1 / 1

Ataxin-7 Antibody (A302-638A) in WB

Detection of human Ataxin-7 by western blot. Samples: Whole cell lysate (5, 15 and 50 µg) from HEK293T cells. Antibodies: Affinity purified rabbit anti-Ataxin-7 antibody (Product # A302-638A) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.

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Immunogen image

Immunogen Image Ataxin-7 Polyclonal Antibody

产品信息

A302-638A

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Region between residue 842 and 892 of human spinocerebellar ataxia type 7.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

tris citrate/phosphate, pH 7-8

内含物

0.09% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

The recommended shelf life for this product is 1 year from date of receipt.

靶标信息

Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death.

仅用于科研。不用于诊断过程。未经明确授权不得转售。