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Invitrogen
Aurora A Polyclonal Antibody
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产品信息
PA5-19459
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Aurora A.
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA5-19459 targets Aurora A in ICC, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-19459 immunogen is synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Aurora A.
PA5-19459 detects Aurora A which has a predicted molecular weight of approximately 46 kDa.
靶标信息
AURKA (Aurora A) is a serine/threonine kinase that regulates mitosis by association in vivo with centrosomes. Overexpression of AURKA is observed in many types of cancer. Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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