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Proteintech
BAAT Polyclonal Antibody
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产品信息
15990-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BAAT Fusion Protein Ag8860 (1-418 aa encoded by BC009567)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MIQLTATPV SALVDEPVHI QATGLIPFQM VSFQASLEDE NGDMFYSQAH YRANEFGEVD LNHASSLGGD YMGVHPMGLF WSLKPEKLLT RLLKRDVMNR PFQVQVKLYD LELIVNNKVA SAPKASLTLE RWYVAPGVTR IKVREGRLRG ALFLPPGEGL FPGVIDLFGG LGGLLEFRAS LLASRGFASL ALAYHNYEDL PRKPEVTDLE YFEEAANFLL RHPKVFGSGV GVVSVCQGVQ IGLSMAIYLK QVTATVLING TNFPFGIPQV YHGQIHQPLP HSAQLISTNA LGLLELYRTF ETTQVGASQY LFPIEEAQGQ FLFIVGEGDK TINSKAHAEQ AIGQLKRHGK NNWTLLSYPG AGHLIEPPYS PLCCASTTHD LRLHWGGEVI PHAAAQEHAW KEIQRFLRKH LIPDVTSQL (1-418 aa encoded by BC009567 )
靶标信息
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BACAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA thioesterase; Bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; Choloyl-CoA hydrolase; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase; taurine N-acyltransferase
基因别名: AI118337; AI158864; BAAT; BACAT; BAT
UniProt ID: (Human) Q14032, (Mouse) Q91X34
Entrez Gene ID: (Human) 570, (Mouse) 12012
receptor binding
protein binding
palmitoyl-CoA hydrolase activity
N-acyltransferase activity
transferase activity, transferring acyl groups
glycine N-choloyltransferase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
transferase activity
hydrolase activity
thiolester hydrolase activity
esterase
hydrolase
metabolite interconversion enzyme
