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Invitrogen
BACE2 Polyclonal Antibody
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产品信息
PA5-148648
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse BACE-2, Phe29-Pro462 (Tyr357His)
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: asp 1; ASP1; Aspartyl protease 1; be; beta secretase 2; Beta-secretase 2; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase
基因别名: 1110059C24Rik; AEPLC; AI850424; ALP56; ARP1; ASP21; Bace2; BAE2; CDA13; CEAP1; DRAP
UniProt ID: (Mouse) Q9JL18
Entrez Gene ID: (Mouse) 56175
