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Invitrogen
BAD Polyclonal Antibody
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产品信息
PA1-29470
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment, corresponding to amino acids 2-168 of Human Bad.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-29470 detects Bad from human samples.
PA1-29470 has been successfully used in Western blot applications.
The PA1-29470 immunogen is: Recombinant fragment, corresponding to amino acids 2-168 of Human Bad.
靶标信息
The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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