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Proteintech
BAG1 Polyclonal Antibody
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产品信息
19064-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BAG1 Fusion Protein Ag13555 (36-345 aa encoded by BC014774)
偶联物
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can recognize all the isoforms of BAG1.
Immunogen sequence: PAQRGPPPS RRPPARSTAS GHDRPTRGAA AGARRPRMKK KTRRRSTRSE ELTRSEELTL SEEATWSEEA TQSEEATQGE EMNRSQEVTR DEESTRSEEV TREEMAAAGL TVTVTHSNEK HDLHVTSQQG SSEPVVQDLA QVVEEVIGVP QSFQKLIFKG KSLKEMETPL SALGIQDGCR VMLIGKKNSP QEEVELKKLK HLEKSVEKIA DQLEELNKEL TGIQQGFLPK DLQAEALCKL DRRVKATIEQ FMKILEEIDT LILPENFKDS RLKRKGLVKK VQAFLAECDT VEQNICQETE RLQSTNFALA E (36-345 aa encoded by BC014774)
靶标信息
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
基因别名: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to lithium ion
response to organic cyclic compound
response to nicotine
response to drug
cell surface receptor signaling pathway
regulation of catalytic activity
regulation of cellular response to heat
