The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
蛋白别名: B-cell scaffold protein with ankyrin repeats; B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript; Protein AVIEF
基因别名: A530094C12Rik; AI451642; AVIEF; BANK; BANK1; LRRGT00104