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Abnova
BATF Polyclonal Antibody, MaxPab™
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BATF Antibody (H00010538-D01P) in WB
Western Blot analysis of BATF expression in transfected 293T cell line (H00010538-T02) by BATF MaxPab polyclonal antibody.
Lane 1: BATF transfected lysate(14.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: BATF transfected lysate(14.10 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00010538-D01P
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BATF (NP_006390.1, 1 a.a. approximately 125 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MPHSSDSSDS SFSRSPPPGK QDSSDDVRRV QRREKNRIAA QKSRQRQTQK ADTLHLESED LEKQNAALRK EIKQLTEELK YFTSVLNSHE PLCSVLAAST PSPPEVVYSA HAFHQPHVSS PRFQP
靶标信息
BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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