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Rockland
BATF3 Polyclonal Antibody
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BATF3 Antibody (600-401-Z36) in ICC/IF
Immunofluorescence Microscopy of Rabbit anti-BATF3 antibody. Tissue: rat kidney. Primary antibody: BATF3 antibody at 20 µg/mL. Secondary antibody: Fluorescein rabbit secondary antibody at 1:20,000. Localization: BATF3 is nuclear. Staining: BATF3 as red fluorescent signal.
产品信息
600-401-Z36
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-BATF3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the N-terminus of human BATF3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
BATF3, also known as SNFT, belongs to the basic leucine zipper transcriptional family and functions as a transcriptional repressor when heterodimerizing with Jun and can repress the transcription of IL-2 and MMP-1. BATF3 is required for the development of CD8alpha+ classical dendritic cells (DCs) and the related CD103+ DCs that cross-present antigens to CD8 T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 21 kDa small nuclear factor isolated from T-cells; 21-kD small nuclear factor isolated from T cells; B-ATF-3; basic leucine zipper transcription factor, ATF-like 3; Basic leucine zipper transcriptional factor ATF-like 3; JDP-1; Jun dimerization protein 1; Jun dimerization protein p21SNFT
基因别名: 9130211I03Rik; BATF3; JDP1; JUNDM1; SNFT
UniProt ID: (Human) Q9NR55, (Rat) P97876, (Mouse) Q9D275
Entrez Gene ID: (Human) 55509, (Rat) 60462, (Mouse) 381319
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
DNA binding
sequence-specific DNA binding
protein heterodimerization activity
basic leucine zipper transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
response to virus
myeloid dendritic cell differentiation
dendritic cell differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
cell differentiation
