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Proteintech
BBOX1 Polyclonal Antibody
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产品信息
16099-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BBOX1 Fusion Protein Ag8964 (1-387 aa encoded by BC011034)
偶联物
形式
Liquid
浓度
0.36 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MACTIQKAE ALDGAHLMQI LWYDEEESLY PAVWLRDNCP CSDCYLDSAK ARKLLVEALD VNIGIKGLIF DRKKVYITWP DEHYSEFQAD WLKKRCFSKQ ARAKLQRELF FPECQYWGSE LQLPTLDFED VLRYDEHAYK WLSTLKKVGI VRLTGASDKP GEVSKLGKRM GFLYLTFYGH TWQVQDKIDA NNVAYTTGKL SFHTDYPALH HPPGVQLLHC IKQTVTGGDS EIVDGFNVCQ KLKKNNPQAF QILSSTFVDF TDIGVDYCDF SVQSKHKIIE LDDKGQVVRI NFNNATRDTI FDVPVERVQP FYAALKEFVD LMNSKESKFT FKMNPGDVIT FDNWRLLHGR RSYEAGTEIS RHLEGAYADW DVVMSRLRIL RQRVENGN (1-387 aa encoded by BC011034)
靶标信息
BBOX1 encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase); Gamma-BBH; Gamma-butyrobetaine dioxygenase; Gamma-butyrobetaine hydroxylase; Gamma-butyrobetaine,2-oxoglutarate dioxygenase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
基因别名: AI874739; BBH; BBOX; BBOX1; G-BBH; gamma-BBH
UniProt ID: (Human) O75936, (Rat) Q9QZU7, (Mouse) Q924Y0
Entrez Gene ID: (Human) 8424, (Rat) 64564, (Mouse) 170442
iron ion binding
protein binding
zinc ion binding
gamma-butyrobetaine dioxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxidoreductase activity
metal ion binding
dioxygenase activity
hydroxylase
