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Immunogen sequence: MACTIQKAEA LDGAHLMQIL WYDEEESLYP AVWLRDNCPC SDCYLDSAKA RKLLVEALDV NIGIKGLIFD RKKVYITWPD EHYSEFQADW LKKRCFSKQA RAKLQRELFF PECQYWGSEL QLPTLDFEDV LRYDEHAYKW LSTLKKVGIV RLTGASDKPG EVSKLGKRMG FLYLTFYGHT; Positive Samples: U-251MG, MCF7, BT-474, Mouse liver, Mouse kidney, Mouse spinal cord; Cellular Location: Cytoplasm
BBOX1 encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase); Gamma-BBH; Gamma-butyrobetaine dioxygenase; Gamma-butyrobetaine hydroxylase; Gamma-butyrobetaine,2-oxoglutarate dioxygenase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
基因别名: AI874739; BBH; BBOX; BBOX1; G-BBH; gamma-BBH
UniProt ID: (Human) O75936, (Rat) Q9QZU7, (Mouse) Q924Y0
Entrez Gene ID: (Human) 8424, (Rat) 64564, (Mouse) 170442
分子生物学功能: hydroxylase