Proteintech

BBS4 Polyclonal Antibody

19 篇参考文献

查看其他9个BBS4抗体

问题与答案

问题与答案

问题与答案

抗体检测数据 (8)

BBS4 Antibody in Immunocytochemistry (ICC/IF)

BBS4 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 8

BBS4 Antibody (12766-1-AP) in ICC/IF

IF result (cytoplasm and the length of cilia cilia stain) of anti-BBS4 (12766-1-AP; 1:50) with serum-starved hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim.

BBS4 Antibody in Immunocytochemistry (ICC/IF)

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

Product Image Gallery

BBS4 Antibody in Immunocytochemistry (ICC/IF) — IF result (cytoplasm and the length of cilia cilia stain) of anti-BBS4 (12766-1-AP; 1:50) with serum-starved hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim.

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney using 12766-1-AP (BBS4 antibody) at dilution of 1:50 (under 40x lens).

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney using 12766-1-AP (BBS4 antibody) at dilution of 1:50 (under 10x lens).

BBS4 Antibody in Western Blot (WB) — HEK-293 cell lysates were subjected to SDS PAGE followed by western blot with (Product # 12766-1-AP) BBS4 antibody at dilution of 1:2,000 incubated at room temperature for 1.5 hours.

BBS4 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 12766-1-AP (BBS4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

BBS4 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 12766-1-AP (BBS4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

BBS4 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 12766-1-AP (BBS4 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

BBS4 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 12766-1-AP (BBS4 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Immunogen image

BBS4 Polyclonal Antibody

Immunogen Image BBS4 Polyclonal Antibody

产品信息

12766-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看9篇已发表文章 9篇已发表文章

免疫组化（石蜡） (IHC (P))

1:20-1:200

-

免疫细胞化学 (ICC/IF)

1:20-1:200

查看10篇已发表文章 10篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

BBS4 Fusion Protein Ag3430 (1-351 aa encoded by BC027624)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.14 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MAEERVATR TQFPVSTESQ KPRQKKAPEF PILEKQNWLI HLHYIRKDYE ACKAVIKEQL QETQGLCEYA IYVQALIFRL EGNIQESLEL FQTCAVLSPQ SADNLKQVAR SLFLLGKHKA AIEVYNEAAK LNQKDWEISH NLGVCYIYLK QFNKAQDQLH NALNLNRHDL TYIMLGKIHL LEGDLDKAIE VYKKAVEFSP ENTELLTTLG LLYLQLGIYQ KAFEHLGNAL TYDPTNYKAI LAAGSMMQTH GDFDVALTKY RVVACAVPES PPLWNNIGMC FFGKKKYVAA ISCLKRANYL APFDWKILYN LGLVHLTMQQ YASAFHFLSA AINFQPKMGE LYMLLAVALT NL (1-351 aa encoded by BC027624)

靶标信息

BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Bardet-Biedl syndrome 4 homolog; Bardet-Biedl syndrome 4 protein; Bardet-Biedl syndrome 4 protein homolog; BBSome complex member BBS4

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基因别名: AW537059; AW742241; BBS4; D9Ertd464e

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UniProt ID: (Human) Q96RK4, (Mouse) Q8C1Z7

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Entrez Gene ID: (Human) 585, (Mouse) 102774, (Rat) 300754

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RNA polymerase II repressing transcription factor binding microtubule motor activity protein binding dynactin binding alpha-tubulin binding beta-tubulin binding molecular_function

microtubule cytoskeleton organization mitotic cytokinesis neural tube closure retina homeostasis negative regulation of systemic arterial blood pressure transport spermatid development sensory perception of smell protein localization metabolic process negative regulation of gene expression protein transport dendrite development regulation of lipid metabolic process ventricular system development striatum development hippocampus development cerebral cortex development cell projection organization adult behavior negative regulation of actin filament polymerization regulation of cytokinesis leptin-mediated signaling pathway protein localization to organelle negative regulation of GTPase activity microtubule anchoring at centrosome nonmotile primary cilium assembly social behavior photoreceptor cell outer segment organization negative regulation of appetite by leptin-mediated signaling pathway positive regulation of multicellular organism growth cilium assembly response to leptin photoreceptor cell maintenance positive regulation of cilium assembly retinal rod cell development brain morphogenesis centrosome organization maintenance of protein location in nucleus regulation of stress fiber assembly cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility face development fat pad development protein localization to cilium protein localization to centrosome regulation of nonmotile primary cilium assembly protein localization to photoreceptor outer segment neuron migration heart looping visual perception melanosome transport fat cell differentiation intracellular transport sensory processing biological_process