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产品信息
PA5-17951
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (RKLEPPPVKQAEL) corresponding to the C-terminus amino acids of BCAR3
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_10983831
产品详细信息
This antibody is predicted to react with bovine, canine, human and porcine based on sequence homology.
靶标信息
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
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生物信息学
蛋白别名: breast cancer anti-estrogen resistance protein 3; Breast cancer anti-estrogen resistance protein 3 homolog; KIAA0554; OTTHUMP00000011961; p130Cas-binding protein AND-34
基因别名: AI131758; AND-34; And34; Bcar3
UniProt ID: (Mouse) Q9QZK2
Entrez Gene ID: (Mouse) 29815
