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Proteintech
BCAS1 Polyclonal Antibody
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产品信息
25776-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BCAS1 Fusion Protein Ag22760 (1-289 aa encoded by BC126348)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGNQMSVPQ RVEDQENEPE AETYKDNASA LNGVPVVVST HTVQHLEEVD LGISVKTDNV ATSSPETTEI SAVADANGKN LGKEAKPEAP AAKSRFFLML SRPVPGRTGD QAADSSLGSV KLDVSSNKAP ANKDPSESWT LPVAAGPGQD TDKTPGHAPA QDKALSAARD PTLLPPETGG AGGEAPSKPK DSSFFDKFFK LDKGQEKVPG DSQQEAKRAE HQDKVDEVPG LSGQSDDVPA GKDIVDGKEK EGQELGTADC SVPGDPEGLE TAKDDSQAAA IAENNNSIMS (1-289 aa encoded by BC126348)
靶标信息
BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amplified and overexpressed in breast cancer; amplified in breast cancer 1; Breast carcinoma-amplified sequence 1; Breast carcinoma-amplified sequence 1 homolog; Novel amplified in breast cancer 1; Novel amplified in breast cancer 1 homolog
基因别名: 2210416M21Rik; 9030223A09Rik; AI841227; AIBC1; BCAS1; NABC1
UniProt ID: (Human) O75363, (Mouse) Q80YN3
Entrez Gene ID: (Human) 8537, (Mouse) 76960
