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Positive control: HepG2 cell lysate, HT-29 cell lysate, COLO205 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, Mouse liver tissue lysate, Mouse brain tissue lysate, Mouse heart tissue lysate, Rat liver tissue lysate, Rat brain tissue lysate, Rat heart tissue lysate, human colon tissue, human kidney tissue, rat spleen tissue.
Subcellular location: Mitochondrion inner membrane, Mitochondrion matrix.
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and -3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); b-hydroxybutyrate dehydrogenase; BDH; D-beta-hydroxybutyrate dehydrogenase, mitochondrial; MGC2723; MGC4347; MGC9788; Short chain dehydrogenase/reductase family 9C member 1; short chain dehydrogenase/reductase family 9C, member 1
基因别名: 2310032J20Rik; AI327223; BDH; BDH1; SDR9C1
UniProt ID: (Human) Q02338, (Rat) P29147, (Mouse) Q80XN0
Entrez Gene ID: (Human) 622, (Rat) 117099, (Mouse) 71911