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Bethyl Laboratories
BIG2/ARFGEF2 Polyclonal Antibody
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产品信息
IHC-00545
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 300 and 350 of human brefeldin A-inhibited 2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2).
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee and Crab-eating macaque
靶标信息
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor guanine nucleotide-exchange factor 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange protein 2
基因别名: ARFGEF2; ARFGEP2; BIG2; dJ1164I10.1; PVNH2
UniProt ID: (Human) Q9Y6D5
Entrez Gene ID: (Human) 10564
receptor recycling
exocytosis
Golgi to plasma membrane transport
endosome organization
endomembrane system organization
protein transport
regulation of ARF protein signal transduction
positive regulation of tumor necrosis factor production
intracellular signal transduction
positive regulation of GTPase activity
